After a Sub-total Thyroidectomy, patients are at risk for developing which serious condition?

After a subtotal thyroidectomy, patients are particularly at risk for developing thyroid storm due to the disruption of thyroid hormone regulation. This condition represents a hyperthyroid crisis where there is an excessive release of thyroid hormones, often precipitated by stress, infection, or surgical manipulation of the thyroid. In the context of surgery, this is especially relevant because tissue handling may release stored hormones into circulation, leading to an overstimulation of tissues and systems throughout the body.

Symptoms of thyroid storm can include fever, tachycardia, restlessness, and altered mental status, making it a critical condition that requires immediate medical attention. While postoperative changes may also lead to some degree of hypothyroidism eventually or even the emergence of thyroid issues that could lead to thyroid cancer or Graves' disease later in life, the acute risk associated with the surgical procedure primarily focuses on the potential for a thyroid storm, which can be life-threatening if not promptly addressed.