Patients taking Zoloft should avoid which of the following?

St. John's wort is a herbal supplement that is often used for its potential antidepressant effects. However, it is known to interact with numerous medications, including SSRIs like Zoloft (sertraline). This interaction can lead to a serious condition known as serotonin syndrome, which occurs when there is an excess of serotonin in the brain. Symptoms of serotonin syndrome can include agitation, confusion, rapid heart rate, and muscle rigidity, among others.

Patients taking Zoloft should avoid St. John's wort to prevent this potentially dangerous interaction and ensure the safe and effective use of their prescribed medication. This understanding of the interactions between herbal supplements and prescription medications is crucial for patient safety and effective treatment outcomes.