What are the symptoms of Cushing's syndrome commonly associated with?

Cushing's syndrome is commonly associated with the use of glucocorticoids, which are also referred to as "SONES." The term "SONES" is derived from medication names that often have the suffix "-sone," indicating their corticosteroid nature, such as prednisone, dexamethasone, and hydrocortisone. These medications mimic cortisol, which is produced by the adrenal glands, and when taken in excessive amounts or over a prolonged period, they can lead to symptoms of Cushing's syndrome.

Symptoms of Cushing's syndrome include characteristics such as weight gain (especially around the abdomen and face), purple striae on the skin, hypertension, hyperglycemia, and mood changes. The overexposure to corticosteroids from medications can disrupt normal cortisol regulation and cause these typical symptoms, making "SONES" a directly relevant factor in the development of Cushing's syndrome.