What is the therapeutic range for aminophylline?

The therapeutic range for aminophylline is indeed considered to be 10-20 mcg/mL. This range is critical for ensuring the medication is effective while minimizing the risk of toxicity. Aminophylline is a xanthine derivative used primarily for respiratory diseases such as asthma or COPD. When levels fall below 10 mcg/mL, the drug may not achieve the desired therapeutic effects, leading to ineffective management of bronchospasm. Conversely, levels above 20 mcg/mL can increase the risk of adverse effects, including central nervous system stimulation, cardiovascular complications, and gastrointestinal disturbances. Monitoring levels within this range helps healthcare providers maintain safety and efficacy in patient treatment.